Department of Chemistry
Charles Johnson

Charles Johnson

Professor
charles_johnson@unc.edu
919-966-5229
919-962-2388 (fax)
Caudill 018

 

Not Accepting Doctoral Students

Research Interests

Biomedical applications of NMR and Electrophoretic Light Scattering (ELS)

Professional Background

Ph.D.,Massachusetts Institue of Technology (1961); B.S., Georgia Institute of Technology (1958); Alfred P. Sloan Research Fellowship, (1966-72); John Simon Guggenheim Fellowship, (1972-73); Elected Fellow of the American Physical Society, (1975); Elected Fellow of American Association for the Advancement of Science (AAAS) (1991)

Research Synopsis

My goals in research and scholarly work are the following. First, I am collaborating with Prof. Don Gabriel in the development of cell based assays. Current work is focused on the determination of the state of activation of platelet membranes. We are using electrophoretic light scattering (ELS) to monitor the surface charge density of platelets exposed to various agonists. The results can indicate the effectiveness of medications. Instrumentation is under development to automate our procedures. We are also using high-resolution NMR to monitor cellular components for platelets from patients in pilot studies involving anti-platelet and anti-coagulant medications and polyunsaturated fatty acids. Our aim is to obtain information permitting appropriate, individualized recommendations for dietary supplements and medication.

In my second project, I am researching the science behind photography at all levels. I am writing a book on science in photography from quantum mechanics to physiology and art appreciation. The aim is twofold. First, I am using photography as a vehicle to teach science, and second I am helping photographers understand limitations on their ability to acquire images that are imposed by the laws of nature. This work has taken me through the laws of optics, the physics of digital sensors, the physiology of the eye, the perception of color, and now to the psychology of art.