Department of Chemistry

Mass Spectrometry Lab

Equipment Image

The UNC Department of Chemistry Mass Spectrometry facility specializes in small molecule analysis. Our services include, but are not limited to, quantitative mass spectrometry, liquid chromatography separations, fragmentation and structural elucidation mass spectrometry, complex mixture analysis, high resolution and accurate mass analysis, and MALDI ionization. Our facility provides individualized user training for undergraduate, graduate, and post-doctoral scholars in the Department of Chemistry.

Additionally, we aim to provide the highest quality mass spectrometric services possible to members of the UNC Chapel Hill Department of Chemistry, UNC campus community and surrounding Research Triangle area.

There are two possible mechanisms for having samples analyzed in our facility. Samples can be submitted for analysis on a fee for service basis or students can run their own samples, following required training, on our instrumentation.

Please contact Dr. Brandie M. Ehrmann for more information. We provide students/scholars with assistance in experimental design, data acquisition, and data analysis


The Mass Spectrometry Facility is located in room 040 on the ground floor of Caudill Laboratories.


Core Hours

Monday through Friday
09:00 AM - 05:00 PM



The Mass Spectrometry Facility is under the direction of Dr. Brandie M. Ehrmann, a mass spectrometrist with expertise in ultra-high resolution mass spectrometry and complex mixture analysis. She is assisted by David Crizer, a departmental graduate assistant. David handles routine analyses, assist with student training, and routine instrument maintenance procedures.

Director Mass Spectroscopy Facility
Brandie M. Ehrmann, Ph.D.
Caudill Laboratories, room 040
Caudill Laboratories, room 052 - Office


Research Assistant
David Crizer
Glish Laboratory Member
Caudill Laboratories, room 323


Sample Submission

Samples should be submitted to the tray marked "Samples In", located in the cabinet just outside of Caudill 040. All samples must be accompanied by an online submission form (TO BE POSTED 01/23/15).

The more information provided about an analyte, the higher quality the results will be. Important information includes, but is not limited to:

  • Empirical Formula
  • Molecular Weight
  • Molecular Structure
  • Primary Sequence (for peptides and proteins)
  • Concentration
  • Conditions under which degradation can occur
  • Presence of buffers and salts

Please contact the Lab Director for training, if you are interested in becoming an open access user.


Mass Spectrometry Facility Rates

The hourly rates for facility use are subject to change, and differ according to the following user categories: Chemistry, UNC-CH, UNC-OFF,and External. The definition of these four categories are as follows:


Definition of Research Service Center Users

Chemistry Faculty including joint appointees without regard to funding source
Memos of Understanding with other Departments
Excludes non-Chemistry faculty who are co-principal investigators

UNC-CH Departments not covered under Chemistry

UNC Departments not on the Chapel Hill campus

Other non-UNC Universities
Government Laboratories
Commercial businesses


Instrument Use Charges

  Chemistry UNC-CH UNC-OFF External
Prime Time $36.88 $42.71 $46.12 $150.00
Off Hours $12.81 N/A N/A N/A

Prime time is defined by the building open and close hours, currently 7:00 AM to 7:00 PM


Hourly Rates - Consulting Services

  Chemistry UNC-CH UNC-OFF External
Consultation $74.95 $88.40 $96.29 $150.00


Typical Full Service Analysis

All charges are determined by the hour - both instrument and staff time charges apply.

  • MS (Direct infusion ESI)
  • HRMS-I (Direct infusion ESI, <20 ppm accuracy)
  • HRMS-II (Direct infusion ESI, <5 ppm accuracy)
  • MSMS (Nano-ESI, low res)
  • ICPMS (Solution based; direct infusion)
  • MALDI-MS (Nd:YAG Laser 355 nm; 9.4T FTMS)