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ACGS Board of Directors

ACGS Board

The goal of the Association of Chemistry Graduate Students, ACGS, is to provide opportunities and events which promote interaction, fellowship, and camaraderie among graduate students, post-docs, faculty, and staff in the chemistry department.

We organize and sponsor numerous events including a department-wide volleyball tournament, various socials throughout the year, and charity events such as Trivia Night and the Toys for Tots campaign. Feel free to email us at acgs.secretary@gmail.com with any ideas, comments, or questions, especially with regard to improving how we can best serve you and the chemistry community.

Contact any of this year's officers to learn how you can get involved:

President: Katie Moga
Vice-President: Nathan Rodeberg
Treasurer: William Black
Secretary: Colleen O'Neill

 

Face-to-Face Molecules

New research from the You Group, in collaboration with researchers at NCSU, reveals that energy is transferred more efficiently inside of complex, three-dimensional organic solar cells when the donor molecules align face-on, rather than edge-on, relative to the acceptor. This finding may aid in the design and manufacture of more efficient and economically viable organic solar cell technology.

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The paper appears online in Nature Photonics. Fellow NC State collaborators were John Tumbleston, Brian Collins, Eliot Gann, and Wei Ma. Liqiang Yang and Andrew Stuart from UNC-Chapel Hill also contributed to the work. The work was funded by the U.S. Department of Energy, Office of Science, Basic Energy Science, the Office of Naval Research, and the National Science Foundation.

 

Ex Vivo Quantification of PTP

Published in Analytical Chemistry, scientists in the Allbritton Group in collaboration with colleagues from Pharmacology, Biostatistics and Endodontics, and Biomedical Engineering, all at UNC, and the National Health and Environmental Effects Research Laboratory, describe a novel method for the measurement of protein tyrosine phosphatase, PTP, activity in single human airway epithelial cells, hAECs, using capillary electrophoresis.

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Their technique involved the microinjection of a fluorescent phosphopeptide that is hydrolyzed specifically by PTPs. Initial results were then extended to a more physiologically relevant model system: primary hAECs cultured from bronchial brushings of living human subjects. The results demonstrate the utility and applicability of this technique for the ex vivo quantification of PTP activity in small, heterogeneous, human cells and tissues.

 

Biodegradable Memory

Assistant Professor Scott Warren, a joint faculty member with the Department of Chemistry and the Applied Physical Sciences Department here at UNC, is one of the co-authors of an article, published in Angewandte Chemie, describing how single crystals of a cyclodextrin-based metal–organic framework, MOF, infused with an ionic electrolyte and flanked by silver electrodes act as memristors. The article is highlighted in ChemistryWorld, where the invention is referred to as "Computer Memory Made From Sugar Cube."

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Tony Kenyon, an electronic engineer at University College London, says the sugar-cube memory’s performance would not be compatible with existing complementary metal oxide semiconductor, CMOS, technology, the staple of modern computing. But he also points out that other applications could be very interesting. The authors comment that commercial RRAMs have faster read and write times, but state they believe they can make this type of memory cheaper and most definitely greener. The researchers are thinking along the lines of "biodegradable memory."

 

Most Read Articles of 2013

An article titled "Catalytic Hydrotrifluoromethylation of Styrenes and Unactivated Aliphatic Alkenes via an Organic Photoredox System," published in the journal Chemical Science by Professor David Nicewicz, his postdoctoral assistant Dale Wilger, and graduate student Nathan Gesmundo, has been listed as one of the 25 most read articles of 2013.

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Chemical Science is the Royal Society of Chemistry's flagship journal, publishing research articles of exceptional significance and high-impact reviews from across the chemical sciences. Research in Chemical Science is not only of the highest quality but also has excellent visibility.

 

Fluorous Enzymatic Synthesis

As presented in Chemical Communications, researchers in the Allbritton Group in collaboration with Qisheng Zhang, associate professor in UNC's School of Pharmacy, and his group, have published a fluorous tagging strategy coupled with enzymatic synthesis to efficiently synthesize multiple phosphatidylinositides (PIs). PIs and their derivatives are notorious for their structural complexity, with seven stereogenic centers and the hydroxyl groups around the inositol head unit having similar reactivity.

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Most synthetic strategies require selective protection and deprotection of the hydroxyl groups, and usually take more than 15 steps to synthesize one PI. The work presented by the two groups introduces "fluorous enzymatic synthesis," where tandem enzymatic reactions are used to generate multiple probes after purification through fluorous solid phase extraction. These probes can then be used as enzyme reporters, or be directly immobilized on a fluorous surface to form a microarray to investigate protein-small molecule interactions. This strategy should also be applicable to other complex endogenous small molecules whose biosynthetic enzymes are well characterized.

 

Self-Healing Polymer Networks

Self-healing polymeric materials are systems that after damage can revert to their original state with full or partial recovery of mechanical strength. Using scaling theory, researchers in the Rubinstein Group, as published in Macromolecules, studied a simple model of autonomic self-healing of unentangled polymer networks. In this model one of the two end monomers of each polymer chain is fixed in space mimicking dangling chains attachment to a polymer network, while the sticky monomer at the other end of each chain can form pairwise reversible bond with the sticky end of another chain. The group studied the reaction kinetics of reversible bonds in this simple model and analyzed the different stages in the self-repair process.

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The team observed the slowest formation of bridges for self-adhesion after bringing into contact two bare surfaces with equilibrium, very low, density of open stickers in comparison with self-healing. The primary role of anomalous diffusion in material self-repair for short waiting times is established, while at long waiting times the recovery of bonds across fractured interface is due to hopping diffusion of stickers between different bonded partners. Acceleration in bridge formation for self-healing compared to self-adhesion is due to excess nonequilibrium concentration of open stickers. Full recovery of reversible bonds across fractured interface, formation of bridges, occurs after appreciably longer time than the equilibration time of the concentration of reversible bonds in the bulk.

 

 

At the Department of Chemistry, we feel strongly that diversity is crucial to our pursuit of academic excellence, and we are deeply committed to creating a diverse and inclusive community. We support UNC's policy, which states that "the University of North Carolina at Chapel Hill is committed to equality of opportunity and pledges that it will not practice or permit discrimination in employment on the basis of race, color, gender, national origin, age, religion, creed, disability, veteran's status, sexual orientation, gender identity or gender expression."